Tuesday, June 30, 2009

THE EFFECTS OF AQUEOUS EXTRACT FROM Khaya senegalensis ON THE HISTOLOGY OF LIVER AND KIDNEY OF ALBINO RATS

Abstract
Lasisi, E.M. Octoder 2008.
The stem bark of Khaya senegalensis was extracted and administered using aqueous method with the aim determining the effect of Khaya senegalensis (300mg/kg body weight) on liver and kidney of white albino rats. Experimental animals were randomly divided into 7groups with each group consisting of 5rats. Group 7 consists of the control and was orally administered with distilled water. Group 1, 2,3,4,5 and 6 consist of test animal received 300mg/kg dosage of the extracts on repeated basis for different numbers of days for 25days.
The result obtained from the study suggested that prolonged oral administration of aqueous extract from stem bark of Khaya senegalensis showed significant changes on the histology of liver and kidney of white albino rats.

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